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• Cancer (when such diagnosis is end stage or the treatment produces related wasting illness or recalcitrant nausea and vomiting)
• Amyotrophic lateral sclerosis ALS (when such diagnosis is severe or end stage)
• Seizure disorders related to diagnosis of epilepsy or trauma related head injuries
• Multiple sclerosis (when such diagnosis is severe or end stage)
• Crohn’s disease
• Mitochondrial disease
• Parkinson’s disease (when such diagnosis is sever or end stage)
• Sickle cell disease (when such diagnosis is severe or end stage)
• Tourette's syndrome, when such syndrome is diagnosed as severe
• Autism spectrum disorder when (a) patient is 18 years of age or more, or (b) patient is less than 18 years of age and diagnosed with severe autism
• Epidermolysis bullosa
• Alzheimer’s disease (when such disease is severe or end stage)
• AIDS when such syndrome is severe or end stage
• Peripheral neuropathy (when symptoms are severe or end stage)
• Patient is in hospice program (either as inpatient or outpatient)
• Intractable pain
• Post-traumatic stress disorder resulting from direct exposure to or witnessing of a trauma for a patient who is at least 18 years of age

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